They don’t literally check into Seattle Grace. ABC would never allow that. Instead, the Nov. 5 episode — appropriately titled “Changing Channels” — finds the brothers Winchester trapped in some very familiar TV settings. In addition to their Grey’s Anatomy cameo (pictured), Sam and Dean cross over into a CSI-type series as well as a traditional sitcom. Word on the street is that the cheeky Grey’s bit features several nods to the actual ABC drama, including one that Supe fans will find particularly amusing. Guesses?
'Supernatural' first look: Sam and Dean check into Seattle Grace!
- 'Psych': Join EW/Google+ Hangout at 11:15 a.m. ET!
- Beyonce surprise: 'Visual Album' now on iTunes
- 'Grey's Anatomy' recap: 'Get Up, Stand Up'
- 'Scandal' recap: 'A Door Marked Exit'
- Tina + Amy: Darth Vader has two mommies?
- 'Vampire Diaries' recap: 'Fifty Shades of Grayson'
- 'Sing-Off' react: 'Number One Hits'
- 'Reign' midseason finale react: 'Fated'